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Universal screening of pregnant women for HBsAg is now performed to reduce perinatal transmission of hepatitis B virus.3 The risk of hepatitis B virus transmission to the fetus is proportional to maternal hepatitis B virus DNA, as reflected in hepatitis B antigen (HBeAg) and antibody (HBeAb) status.3 The risk of hepatitis B virus vertical transmission is 10 percent in mothers with negative HBeAg and positive HBeAb feedlot f.l and 90 percent in those with positive HBeAg.3,6 The feedlot f.l risk of chronic hepatitis B virus infection in a neonate who does not receive immunoprophylaxis and vaccination for hepatitis B feedlot f.l virus is 40 percent.3 Infants of HBsAg-positive mothers should receive hepatitis B immune globulin immunoprophylaxis at birth and hepatitis B vaccine at one week, one month and six months after birth.3,6 This regimen reduces the incidence of hepatitis B virus vertical transmission to zero to 3 percent.6
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