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Links Effect of cholesterol on macromolecular synthesis and fatty acid uptake by Mycoplasma capricolum.Dahl JS, Dahl CE, Bloch K.The rates of protein and lipid synthesis of Mycoplasma capricolum were essentially synchronous during growth and depended on the sterol supplement in the media increasing in the order cholesterol (0.5 microgram/ml) < lanosterol (10 microgram/ml) < lanosterol (10 microgram/ml) + cholesterol (0.5 microgram/ml) < cholesterol (10 microgram/ml). The effect of lanosterol plus vegan low cholesterol on macromolecular synthesis was synergistic. Whereas protein and lipid vegan synthesis were brought virtually to a halt by cholesterol starvation, DNA synthesis continued for about 8 h. vegan Increasing the palmitate and elaidate concentrations 4-fold in the lanosterol-supplemented media raised the growth rate even in the absence of the small amount of cholesterol (0.5
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