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biopsy is the most sensitive and specific means of evaluating the degree of liver cell injury and hepatic fibrosis.Several reasons justify obtaining a liver biopsy in patients with ALD. Reasons include confirming the diagnosis, excluding other unsuspected causes of liver disease, assessing the perinatalogy extent of liver damage, and defining prognosis.When deciding to perform a biopsy, consider the strength of the perinatalogy clinical diagnosis and the role that the biopsy findings would have in guiding therapeutic options.Histologic Findings: Histologically, fatty liver is characterized by fat accumulation, which is most prominent in the pericentral (centrilobular) zone. Macrovesicular steatosis perinatalogy (Image 1) is the rule; hepatocytes containing one or more large fat droplets displace the nucleus to an eccentric position.
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