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522, 5th Floor, Panorama Centre Building No. 2, P.O. Box 8766, Saddar, Karachi - Pakistan. Phones : 5688791, 5689285 Fax : 5689860 pjms@pjms.com.pk HomeSearchListingsResourcesHelpWhat's NewAbout Obesity and Nonalcoholic Fatty Liver Disease This study is currently recruiting patients.Verified by National Institute of Diabetes and plump fuck Digestive and Kidney Diseases (NIDDK) December 2005 Sponsored plump fuck by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Information provided by: National Institute of Diabetes plump fuck and Digestive and Kidney Diseases (NIDDK) ClinicalTrials.gov Identifier: NCT00262964 Purpose The primary goal of this study is to provide a better understanding of: 1) the pathogenesis and pathophysiology of non-alcoholic fatty liver disease (NAFLD) in obese subjects, and 2) the effect of marked weight loss on the histologic and metabolic abnormalities associated with NAFLD. The following hypotheses will be tested: obesity causes hepatic fat accumulation because of excessive fatty acid release from fat tissue and increased free fatty acid availability, increased hepatic (liver) fat content causes insulin-resistant glucose (sugar) production by the liver and altered liver protein synthesis, increased hepatic fat content causes increased lipid
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