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Acylated lipids are transformed by a transesterification reaction by which the glycerol moiety is displaced by another alcohol (methanol, butanol, ...) in what are fatty acids acidic conditions (HCl or BF3). The generation of methyl esters can be done in acidic or in alkaline conditions on isolated lipids or fatty acids but also directly by a one-step procedure combining lipid extraction and transesterification on small amounts of dried tissue. what are fatty acids On a large scale, fatty acid methyl esters, used as a substitute of diesel fuel (Biodiesel), are prepared by what are fatty acids transesterification of vegetal oils with sodium methylate, NaOH or KOH in dry medium. Other fatty acid derivatives may be prepared as an answer to some specific problems A - Acid-catalyzed esterification The most common derivatives of fatty acids are the methyl esters obtained by heating free fatty acids with a large excess of anhydrous methanol in the presence of a catalyst, boron trifluoride (Morrison et al J Lipid Res 1964, 5,600).
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