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2001 Nov;139(5):650-5. Links Essential fatty acid deficiency in relation gc capillary columns to genotype in patients with cystic fibrosis.Strandvik B, Gronowitz E, Enlund F, Martinsson T, Wahlstrom J.Department of Pediatrics and Clinical Genetics, Faculty of Medicine, Goteborg University, Goteborg, Sweden.OBJECTIVE: To gc capillary columns determine if the serum phospholipid fatty acid pattern in patients with cystic fibrosis (CF) was related to the major cystic fibrosis transmembrane conductance regulator gene mutations. METHODS: Patients with CF (n = 110) aged 3 months to 56 years were studied. Serum samples were analyzed for phospholipid gc capillary columns fatty acid with gas-liquid chromatography, and cystic fibrosis transmembrane conductance regulator mutations were determined with standard methods. RESULTS: Patients with CF had significantly lower molar percentages of linoleic acid and docosahexaenoic acid in the serum phospholipid than healthy controls (mean +/- standard deviation, 20.3
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